What it is

What Is Photodynamic Therapy?

Photodynamic therapy involves administering a photosensitizing agent that accumulates preferentially in cancer cells or diseased tissue. When this compound is activated by exposure to a specific wavelength of light, it produces reactive oxygen species that destroy the targeted cells. Healthy tissue, which absorbs less of the photosensitizer, is largely spared.

Illustration of a photodynamic therapy and intravenous laser blood irradiation device
Illustration: multi-wavelength intravenous laser / photodynamic therapy system. Not a photo of our department.
How it works

How Does It Work?

A photosensitizing agent is administered intravenously or applied topically, depending on the condition being treated. After a defined accumulation period, the treatment area is exposed to light of the appropriate wavelength using fiber optic devices or external light sources. The light activates the photosensitizer within the diseased cells, triggering a localized cytotoxic reaction. The treatment also stimulates local immune responses against the treated tissue.

Who it is for

What Conditions Does It Treat?

  • Various cancer types (surface and accessible tumors)
  • Chronic Lyme disease and persistent infections
  • Precancerous lesions
  • Conditions requiring targeted tissue destruction

Is CES Right for You?

CES is a gentle, well-tolerated treatment that may complement other therapies. Our specialists will assess whether it is appropriate for your condition

In the room

What a session feels like

  1. Before The photosensitizer is given first. Depending on the agent you then wait hours, or in some cases days, for it to accumulate in the target tissue.
  2. During Light exposure lasts 15–45 minutes depending on the area. You feel warmth from the light source; it is generally painless.
  3. Afterwards Your skin and eyes will be light-sensitive for a period we specify. Sunglasses, long sleeves and shade until then.
Evidence

Evidence & Safety

PDT is approved for several cancer indications in multiple countries and has extensive published research supporting its use. Clinical trials have demonstrated effectiveness in various tumor types. St. George Hospital has published research on PDT applications in integrative oncology and has decades of clinical experience with this modality.

Where we use it

Used in These Departments

Request a consultation

A video consultation in English before you travel. A physician reviews your findings first; we reply by email within one business day (Mon–Fri).

Mon–Thu 08:00–17:00, Fri 08:00–14:00 (CET/CEST)+49 8061 398-0info@clinicum-stgeorg.de

St. George Hospital is a specialist hospital, not an emergency department. In a medical emergency in Germany, dial 112.

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