Is this you?

The oncologist has a plan. You want to know what else can be done alongside it.

The diagnosis came with a schedule: surgery, chemotherapy, perhaps radiotherapy, then years of endocrine therapy. You are not trying to replace any of it. You are looking for what supports your body through it, what may help the treatment do its work, and who will look at all of you, with the tumor in its context.

What it is

How the hospital approaches breast cancer

Breast cancer is the most common cancer in women worldwide. Surgery, chemotherapy, radiotherapy, endocrine therapy and HER2-directed drugs are the treatments that have improved survival, and they remain your treatment. What St. George Hospital adds is a program around them: heat where it makes radiation or a drug act harder in the tissue, immune and supportive measures for the months of treatment, and a measurement of the hormonal and metabolic conditions in which the tumor grew.

The program supports patients at three points: during active treatment, where the aim is tolerance and local effect; after treatment, where the aim is a plan for the years of endocrine therapy; and in recurrent or metastatic disease, where additional options are weighed after medical review. Each plan is written by Dr. Martin Rößner, Chief Physician for internal medicine and oncology, with the ward team, and coordinated with your oncologist at home. None of the therapies on this page is offered as a replacement for a treatment your oncologist recommends.

Two women seen from behind sitting close together on a garden bench
How we treat

What the hospital adds at each stage

Local-regional hyperthermia

Radiofrequency applicators heat the breast or chest wall region to 40–44 °C / 104.0–111.2 °F for about 60 minutes, two to three times a week, timed to your chemotherapy or radiotherapy. Its most studied use is recurrent disease on the chest wall treated with radiotherapy.

What local-regional hyperthermia involves

Whole-body hyperthermia

The core temperature is raised under continuous monitoring in a session of four to six hours with a physician and nurse present. Used in metastatic disease alongside systemic treatment; the evidence here is emerging, from cohort and early-phase data.

What a whole-body session involves

IPT low-dose chemotherapy

Insulin first, then a fraction of the standard chemotherapy dose, then glucose, with a physician and nurse at the chair. Considered for women who no longer tolerate full-dose chemotherapy, after consultation with the oncologist. The evidence is limited.

How IPT low-dose chemotherapy works

Mistletoe and immune therapy

Mistletoe (Viscum album) injections two to three times a week, thymus peptides and, for selected patients, dendritic cell therapy, chosen from the immune profile taken on arrival. Mistletoe is the most studied complementary therapy in European oncology.

What immune therapy involves

Hormone and estrogen metabolism

Alongside the endocrine therapy your oncologist prescribes, the laboratory measures how your body metabolizes estrogen (the 2-OH, 4-OH and 16-OH metabolite ratios), progesterone balance and markers of environmental estrogen exposure. Nutrition and supplementation are written from those results.

Infusions and nutrition

High-dose vitamin C and nutrient infusions, liver support, anti-inflammatory nutrition and supplementation (vitamin D, omega-3, curcumin, selenium) are given as supportive measures for the months of treatment. They are supportive, and the hospital says so.

A knitted cap and a folded cotton wrap over a chair arm, a glass of water on the sill
When to come

Support at every stage, and who is excluded

  • Before surgery: immune and nutritional preparation in the weeks before the operation
  • During chemotherapy or radiotherapy: hyperthermia timed to the sessions, side-effect management, immune support
  • After standard treatment: a measured plan for the years of endocrine therapy
  • Recurrent disease on the chest wall: hyperthermia with re-irradiation, coordinated with your radiation oncologist
  • Metastatic disease: hyperthermia, immune and supportive measures alongside systemic treatment
  • Triple-negative disease: hyperthermia around the chemotherapy days, immune and metabolic measures, as an individual concept

The program is not suitable for every patient. Acute medical instability, severe heart disease that rules out hyperthermia, skin that cannot tolerate heat in a previously irradiated field, and a performance status that no longer allows a two-week stay are the usual reasons the physicians advise against traveling. We tell you this in writing after the records review.

A person in a soft knit sweater sits by a tall window of a Bavarian guesthouse

From your records to the follow-up

  1. Before you travel

    After the International Office requests them, the oncology team reads your pathology (receptor status, HER2, grade), imaging and treatment summary. A video consultation and a written cost overview follow.

  2. First two days

    days 1 to 2

    Tumor markers, immune status, the estrogen metabolite panel, vitamin D and organ function. The physician writes the plan with you.

  3. During the stay

    Hyperthermia around your chemotherapy or radiotherapy dates, mistletoe injections from the first week, the plan adjusted from week-two measurements. A physician sees you every day.

  4. Discharge

    A report for your oncologist at home and a supplementation plan. Follow-up questions go to the International Office.

Integrative oncology program in Germany

How strong the evidence is for each addition

Hyperthermia added to radiotherapy in recurrent breast cancer rests on strong evidence for local control, mistletoe on moderate evidence for quality of life. No trial shows longer survival from hyperthermia, and the hospital does not claim it.

Read the evidence in detail

Evidence is graded on this page in four words: strong, moderate, emerging and limited. A component graded limited or emerging is an individual treatment attempt decided with the patient after medical consultation, and the physician says so before you consent.

Hyperthermia with radiotherapy in recurrent breast cancer: strong. Five randomized trials in 306 patients with recurrent or inoperable primary breast cancer found complete responses in a larger share of patients when hyperthermia was added to radiotherapy, with the greatest effect in recurrences in previously irradiated areas where only low radiation doses were possible (Vernon et al., Int J Radiat Oncol Biol Phys, 1996). A randomized trial of superficial tumors with measured thermal dose found the same local-control benefit, and no overall survival benefit (Jones et al., J Clin Oncol, 2005). A meta-analysis of 34 studies in locoregional recurrent breast cancer confirmed the higher complete-response rate with hyperthermia added (Datta et al., Int J Radiat Oncol Biol Phys, 2016).

Mistletoe: moderate for quality of life. A meta-analysis of nine randomized trials in breast cancer found a medium-sized improvement in quality of life with mistletoe extracts (Loef et al., Integr Cancer Ther, 2023). Mind-body and supportive measures: the Society for Integrative Oncology guideline recommends meditation, yoga, relaxation and music therapy for anxiety and mood during breast cancer treatment and acupressure or acupuncture for chemotherapy-induced nausea, and finds no strong evidence for ingested supplements against treatment side effects (Greenlee et al., CA Cancer J Clin, 2017); the American Society of Clinical Oncology endorsed that guideline (Lyman et al., J Clin Oncol, 2018). Whole-body hyperthermia, IPT, dendritic cell therapy and the estrogen metabolism work: emerging to limited.

What the evidence does not show is longer survival from hyperthermia in breast cancer: the randomized trials measured local control, and the hospital does not claim more than they found. The article on mistletoe therapy in cancer in our journal goes through the mistletoe trials in more detail.

Costs and billing

Treatment at St. George Hospital is self-pay. Costs are individual: a package price plus individual add-ons, set out in a written, itemized cost overview after a physician has read your findings. A deposit is paid before admission. After the stay you receive an itemized invoice in English that you can submit to your insurer; reimbursement is not promised. Details are on costs and insurance.

Traveling here

Patients from more than 60 countries have been treated on the ward. Munich Airport is about 60 minutes by car; the International Office arranges the transfer (charged extra), accommodation for a companion and the video consultation before you travel. The practical side is under information for international patients.

FAQ

Questions patients ask about breast cancer treatment here

Can I come during chemotherapy or radiotherapy?

Yes, in most cases. Hyperthermia is meant to act together with the drug or the radiation, so the physician schedules sessions around your infusion or radiotherapy dates. Bring the treatment plan and the date of your last cycle. Certain regimens can be continued on the ward after coordination with your oncologist; blood counts are checked before every session that could affect them.

Does hyperthermia work for breast cancer?

For recurrent breast cancer on the chest wall treated with radiotherapy, the evidence is strong: five randomized trials and a later meta-analysis found complete responses more often when hyperthermia was added. For primary tumors and for metastatic disease the evidence is emerging, from cohort and early-phase data, and the hospital says so before you consent.

Do you treat triple-negative breast cancer?

Yes. Triple-negative tumors have no hormone receptor or HER2 target, so standard treatment is chemotherapy, sometimes with immunotherapy. Our program adds hyperthermia around the chemotherapy days and immune and supportive measures. The evidence for these additions in triple-negative disease specifically is limited, and the plan is written as an individual concept after medical review.

Will you change my endocrine therapy?

No. Tamoxifen, aromatase inhibitors and other endocrine drugs stay as your oncologist prescribed them. What the hospital adds is a measurement of how your body metabolizes estrogen, vitamin D and inflammatory markers, and nutritional and supplementation advice written from those results, which your oncologist receives in the discharge report.

What does mistletoe therapy do?

Mistletoe extract is injected under the skin two to three times a week. In breast cancer a meta-analysis of nine randomized trials found a medium-sized improvement in quality of life during treatment. The hospital uses it for that purpose, as a supportive measure, and does not present it as a treatment of the tumor itself.

How much does the breast cancer program cost?

This page lists no prices. After a physician has reviewed your findings, you receive a written, itemized cost overview: a package price plus individual add-ons. Nothing is booked before you have it. Details are on costs and insurance.

If you want to know what the program would add to your treatment plan, send your pathology report, imaging and treatment summary. Dr. Rößner's team reads them before the video consultation and answers in writing.

References

  1. Radiotherapy with or without hyperthermia in the treatment of superficial localized breast cancer: results from five randomized controlled trials. International Collaborative Hyperthermia Group.. Int J Radiat Oncol Biol Phys 1996. PMID 8690639
  2. Randomized trial of hyperthermia and radiation for superficial tumors.. J Clin Oncol 2005. PMID 15860867
  3. Hyperthermia and Radiation Therapy in Locoregional Recurrent Breast Cancers: A Systematic Review and Meta-analysis.. Int J Radiat Oncol Biol Phys 2016. PMID 26899950
  4. Quality of Life in Breast Cancer Patients Treated With Mistletoe Extracts: A Systematic Review and Meta-Analysis.. Integr Cancer Ther 2023. PMID 37888846
  5. Clinical practice guidelines on the evidence-based use of integrative therapies during and after breast cancer treatment.. CA Cancer J Clin 2017. PMID 28436999
  6. Integrative Therapies During and After Breast Cancer Treatment: ASCO Endorsement of the SIO Clinical Practice Guideline.. J Clin Oncol 2018. PMID 29889605

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Mon–Thu 08:00–17:00, Fri 08:00–14:00 German time (CET/CEST); in the US Mon–Thu 2–11 a.m. ET, Fri 2–8 a.m. ET.

Munich Airport (MUC), about 60 minutes by car.

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