Systemic Whole Body Hyperthermia (SWBH)

Systemic Whole Body Hyperthermia (SWBH) | Malignant cells and cancerous tissue are more sensitive to heat than healthy tissue and under certain conditions, they can be selectively destroyed by heat.

How does Systemic Whole Body Hyperthermia work?

Before any patient accepted for SWBH, stringent physical examination controls carried out. Among which ECG, pulmonary function tests, blood coagulation, blood count, blood gases, etc. It carried out in a specially developed unit with intensive care control. SWBH performed under sedation. During the treatment, oxygen saturation, pulse rate, blood pressure, core temperature. As well as electrolytes and blood gases strictly supervised and controlled.

To establish a Ph shift within the tumor area, a high glucose solution is administered intravenously. Simultaneously, an infrared. A light 850-1300 mm wavelength introduced to increase the body temperature. Combining thermal damage with a Ph shift makes certain functions within the tumor cells fail, allowing the tumor cells to become more susceptible to cytostatics (chemotherapy substances).

Which diseases treated with Systemic Whole Body Hyperthermia?

SWBH mainly used in:

SWBH also enhances the effects of adjuvant chemotherapy or radiation treatment

For patients with diffuse lung or liver metastases, distended bone metastases, or bone marrow involvement it recommended administering adjuvant chemotherapy (i.e. Mitomycin, cisplatin, Ifosphamid, etc.). It has been shown that certain cytostatics are heat sensitive and thus an enhancement of the effect can be achieved without using high dosages. The strong toxic side effects that patients may experience while using standard chemotherapy overcome with this form of treatment.

In our hospital, SWBH is frequently carried out in combination with Insulin Potentiated Chemotherapy, as well as with low-dose chemotherapy.

Systemic Whole Body Hyperthermia is also offered for benign diseases:

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