H.E.L.P. Apheresis
Precision Blood Filtration for Chronic Inflammation, Microclots, and Immune Recovery
H.E.L.P. Apheresis stands for Heparin-Induced Extracorporeal Low-Density Lipoprotein Precipitation.
Originally developed for severe lipid disorders, this advanced blood filtration therapy has now become a critical tool in the treatment of chronic inflammatory and vascular conditions — including Long COVID, Lyme disease, chronic fatigue syndrome, and autoimmune dysregulation. At St. George Hospital, we use H.E.L.P. Apheresis as part of our integrative recovery protocols to remove microclots, spike protein residues, autoantibodies, and inflammatory mediators.
How H.E.L.P. Apheresis Works
This therapy filters blood plasma through a specialized precipitation and filtration system:
- Heparin binds to LDL, Lp(a), fibrinogen, and other pro-inflammatory proteins
- The plasma is acidified and cooled to separate pathological components
- A cascade filtration system removes microparticles, cytokines, immune complexes, and coagulation factors
- he clean plasma is rebuffered and reinfusedThis process removes what no medication can — safely and efficiently.
What H.E.L.P. Apheresis Removes
- Fibrin(ogen) and microthrombi
- Spike protein complexes (from virus or vaccine exposure)
- α2-antiplasmin, Factor VIII, and von Willebrand factor
- C-reactive protein (CRP), TNF-α, IL-6
- Autoantibodies, immune complexes, oxidized LDL
- Pro-coagulatory lipoproteins like Lp(a) and oxidized cholesterolThe result is improved microcirculation, oxygen delivery, and immune system reset.

Clinical Indications at St. George Hospital
We use H.E.L.P. Apheresis as part of our integrative programs for:
- Post-COVID Syndrome with confirmed microclot burden or persistent spike protein
- Chronic Lyme disease with vascular involvement or autoimmunity•
- Chronic Fatigue Syndrome / ME
- Autoimmune dysregulation and systemic inflammation
- Cardiovascular patients with high Lp(a), LDL or CRP
In many of our patients, it is the turning point toward symptom relief.
What to Expect
- The procedure takes approx. 2–3 hours
- Blood is drawn through a sterile circuit, processed, and reinfused
- Carried out in a calm, monitored clinical setting by experienced staff
- Most patients receive 2–3 treatments during their stay, depending on findingsFluorescence microscopy and lab diagnostics are used to assess microclot burden before and after.
- Developed in Germany, H.E.L.P. Apheresis has over 30 years of application and is FDA- and CE-approved for lipid apheresis
- Now increasingly used off-label in Post-Viral Syndromes
- Research by Dr. Beate Jaeger and Pretorius et al. has shown that amyloid-like microclots are resistant to fibrinolysis and contribute to vascular hypoxia, immune exhaustion, and chronic symptoms
- These microclots can be clearly visualized under fluorescence microscopy, and reduced after apheresis (Pretorius, 2022)
“When medications fail to remove what’s driving inflammation, we filter it out. H.E.L.P. is not just a therapy — it’s a reset.”
Clinical Director, St. George Hospital

Suffering from unexplained fatigue, brain fog, or long COVID symptoms?
Ask us how H.E.L.P. Apheresis can support your recovery.
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